The University of Georgia
the Boons Group
Publications
Complex Carbohydrate Research Center
158. Ingale, S. M.A. Wolfert, T. Buskas, and G.J. Boons. 2008 Increasing the antigenicity of synthetic tumor-associated carbohydrate antigens by targeting Toll-like receptors. ChemBioChem. In press.
157. Ferrand, Y., E. Klein, N.P. Barwell, M.P. Crump, J. Jimenez-Barbero, C. Vincent, G.J. Boons, S. Ingale, and A.P. Davis. 2008. A synthetic lectin for O-linked b-N-acetylglucosamine (O-GlcNAc). Angew. Chem. Int. Ed. In press.
156. Kuntz, D.A., W. Zhong, J. Guo, D.R. Rose, and G.J. Boons. 2008. The molecular basis of inhibition of golgo mannosidase II by Mannostatin A. ChemBioChem. In press.
155. Park, J., T. Boltje, and G.J. Boons. 2008. Direct and stereoselective synthesis of a-linked 2-deoxy-glycosides. Org. Lett. 10(19): 4367-4370.
154. Zhang, Y., J. Gaekwad, M.A. Wolfert, and G.J. Boons. 2008. Synthetic tetra-acylated derivatives of lipid A from Porphyromonas gingivalis are antagonists of human TLR4. Org. Biomol. Chem. 6(18): 3371-3381.
153. Vohra, Y., M. Vasan, A. Venot, and G.J. Boons. 2008. One-pot synthesis of ologosaccharides by combining reductive openings of benzylidene acetals and glycosylations. Org. Lett. 10(15): 3247-3250.
152. Rauvolfova, J., A. Venot, and G.J. Boons. 2008. Chemo-enzymatic synthesis of C-9 acetylated sialosides. Carbohydr. Res. 34: 1605-1611.
151. Zhong, W., D.A. Kuntz, B. Ember, H. Singh, K.W. Moremen, D.R. Rose, and G.J. Boons. 2008. Probing the substrate specificity of golgi α-mannosidase II using synthetic oligosaccharides and a catalytic nucleophil mutant. J. Am. Chem. Soc. 130(28): 8975-8983.
150. Vasan, M., J. Rauvolfova, M.A. Wolfert, C. Leoff, E.L. Kannenberg, C.P. Quinn, R.W. Carlson, and G.J. Boons. 2008. Chemical synthesis and immunological properties of oligosaccharides derived from the vegetative cell wall of Bacillus anthracis. ChemBioChem. 9(11):1716-1720.
149. Marina-Garcia, N., L. Franchi, Y.G. Kim, D. Miller, C. McDonald, G.J. Boons, and G. Nunez. 2008. Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces Caspase-1 activation via Cryopyrin/NLRP3 independently of Nod2. J. Immunol. 180(6): 4050-4057.
148. Ning, X., J. Guo, M.A. Wolfert, and G.J.Boons. 2008. Visualizing metabolically-labeled glycoconjugates of living cells by copper-free and fast Huisgen cycloadditions. Angew. Chem. Int. Ed . 47(12): 2253-2255. Selected as a VIP paper.
147. Rao, Y., T. Buskas, A. Albert, M.A. O'Neill, M.G. Hahn, and G.J. Boons. 2008. Synthesis and immunological properties of a tetrasaccharide portion of the B-side chain of Rhamnogalacturonan II (RG-II). ChemBioChem. 9(3): 381-388.
146. Zhang, Y., J. Gaekwad, M.A. Wolfert, and G.J. Boons. 2008. Innate immune responses of synthetic lipid A derivatives of Neisseria meningitidis. Chem. Eur. J. 14(2): 558-569.
145. Ingale, S., M.A. Wolfert, J. Gaekwad, T. Buskas, and G.J. Boons. 2007. Robust immune responses elicited by a fully synthetic three-component vaccine. Nature Chem. Biol. 3(10): 663-667. Highlighted in Nature Chemical Biology: Bundle, D.R. 2007. A carbohydrate vaccine exceeds the sum of its parts. Nature Chem. Biol. 3(10): 605-606.
144. Li, X., S. Wang, J. Qi, S.F. Echtenkamp, R. Chatterjee, M. Wang, G.J. Boons, R. Dziarski, and D. Gupta. 2007. Zebrafish peptidoglycan recognition proteins are bactericidal amidases essential for defense against bacterial infections. Immunity. 27: 518-529.
143. Vasan M., M.A. Wolfert, and G.J. Boons. 2007. Agonistic and antagonistic properties of Rhizobium sin-1 lipid A modified by an ether-linked lipid. Org. Biomol. Chem. 5(13): 2087-2097.
142. Rao, Y., and G.J. Boons. 2007. A highly convergent chemical synthesis of conformational epitopes of Rhamnogalacturonan II. Angew. Chem. Int. Ed. 119(32): 6260-6263.
141. Cho, S., Q. Wang, C.P. Swaminathan, D. Hesek, M. Lee, G.J. Boons, S. Mobashery, and R.A. Mariuzza. 2007. Structural insights into the bacterial mechanism of human peptidoglycan recognition proteins. Proc. Natl. Acad. Sci. 104(21): 8761-8766.
140. Zhang, Y., M.A. Wolfert, and G.J. Boons. 2007. The influence of the long chain fatty acid on the antagonistic activities of Rhizobium sin-1 lipid A. Bioorg. Med. Chem. 15(14): 4800-4812.
139. Park, J., S. Kawatkar, J.H. Kim, and G.J. Boons. 2007. Stereoselective glycosylations of 2- azido-2-deoxy-glucosides using intermediate sulfonium ions. Org. Lett. 9(10): 1959-1962.
138. Liu, S., A. Venot, L. Meng, F. Tian, K.W. Moremen, G.J. Boons and J.H. Prestegard. 2007. Spin labeled analogs of CMP-NeuAc as NMR probes of the alpha-2,6-sialyltransferase ST6Gal I. Chem. Biol. 14(4): 409-418.
137. Zhang, Y., J. Gaekwad, M.A. Wolfert, and G.J. Boons. 2007. Modulation of innate immune responses with synthetic lipid A derivatives. J. Am. Chem. Soc. 129(16): 5200-5216.
136. Wolfert, M. A., A. Roychowdhury, and G.J. Boons. 2007. Modifications of the structure of peptidoglycan is a strategy to avoid detection by NOD1. Infect. Immun. 75(2): 706-713. Selected for IAI Spotlight.
135. Ingale, S., T. Buskas, and G.J. Boons. 2006. Synthesis of glyco(lipo)peptides by liposome-mediated native chemical ligation Org. Lett. 8(25): 5785-5788.
134. Mehta, A., E. Saile , W. Zhong, T. Buskas, R. Carlson, E. Kannenberg, Y. Reed, C.P. Quinn, and G.J. Boons. 2006. Synthesis and antigenic analysis of the Bc1A glycoprotein oligosaccharide from Bacillus anthracis exosporium. Chem. Eur. J. 12: 9136-9149. Selected for Frontispiece.
133. Alphey, M.S., A. Burton, M.D. Urbaniak, G.J. Boons, M.A.J. Ferguson, and W.N. Hunter. 2006. Tyrpanosoma brucei UDP-galactose-4’-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4fluoro-α-D-galactose. Sect. F Struct. Biol. Cryst. Commun. 62(9): 829-834.
132. Kim, J.H., H. Yang, V. Khot, D. Whitfield, and G.J. Boons. 2006. Stereoselective glycosylations using (R)- or (S)-(ethoxycarbonyl)benzyl chiral auxiliaries at C-2 of glycopyranosyl donors. Eur. J. Org. Chem. 2006(22): 5007-5028. Selected for cover picture.
131. Zhu, X., S. Kawatkar, Y. Rao, and G.J. Boons. 2006. A practical approach for the stereoselective introduction of beta-arabinofuranosides. J. Amer. Chem. Soc. 128(36): 11948-11957. Highlighted in C&E News: Borman, S. 2007. Bacterial cell wall made. Chemical & Engineering News 85(32): 6.
130. Guo, J., J. Asong, and G.J. Boons. 2006. Selective inhibition of glycosidases by feedback prodrugs. Angew. Chem. Int. Ed. 45: 5345-5348.
129. Kawatkar, S., D.A. Kuntz, R.J. Woods, D.R. Rose, and G.J. Boons. 2006. The structural basis of the inhibition of Golgi alpha-mannosidase II by mannostatin A and the role of the thiomethyl moiety in protein ligand interactions. J. Amer. Chem. Soc. 128(25): 8310-8319.
128. Buts, L., A. Garcia-Pino, A. Imberty, N. Amiot, G.J. Boons, S. Beeckmans, W. Versees, L. Wyns, and R. Loris. 2006. Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin. FEBS Journal. 273: 2407-2420.
127. Guan, R., P.H. Brown, C.P. Swaminathan, A. Roychowdhury, G.J. Boons, and R.A. Mariuzza. 2006. Crystal structure of human peptidoglycan recognition protein Ia bound to a muramyl pentapeptide from Gram-positive bacteria. Protein Science. 15: 1199-1206.
126. Buskas, T., S. Ingale, and G.J. Boons. 2006. Glycopeptides as versatile tools for glycobiology. Glycobiology. 16(8): 113R-136R.
125. Rao, Y., A. Venot, E.E. Swayze, R.H. Griffey and G.J. Boons. 2006. Trisaccharide mimetics of the aminoglycoside antibiotic neomycin. Org. Biomol. Chem. 4(7): 1328-1337.
124. Lee, H.S. , M.A. Wolfert, Y. Zhang, and G.J. Boons. 2006. The 2-aminogluconate isomer of Rhizobium sin-1 lipid A can antagonize TNF-a production induced by enteric LPS. ChemBioChem. 7(1): 140-148.
123. Swaminathan, C.P., P.H. Brown, A. Roychowdhury, Q. Wang, R. Guan, N. Silverman, W.E. Goldman, R.A. Mariuzza and G.J. Boons. 2005. Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs). Proc. Natl. Acad. Sci. 103(3): 684-689.
122. Kumar, S., A. Roychowdhury, B. Ember, Q. Wang, R. Guan, R. Mariuzza, and G.J. Boons. 2005. Selective recognition of synthetic lysine and meso diaminopimelic acid-type peptidoglycan fragments by human peptidoglycan recognition protein-Ialpha and -S. J. Biol. Chem. 280(44): 37005-37012.
121. Roychowdhury, A., M.A. Wolfert, and G.J. Boons. 2005. Synthesis and pro-inflammatory properties of muramyl tripeptides containing lysine and diaminopimelic acid moieties. ChemBioChem. 6: 2088-2097.
120. Buskas, T., Y. Li, and G.J. Boons. 2005. Synthesis of a dimeric Lewis antigen and the evaluation of the epitope specificity of antibodies elicited in mice. Chem. Eur. J. 11(18): 5457-5467.
119. Buskas, T., S. Ingale, and G.J. Boons. 2005. Towards a fully synthetic carbohydrate-based anti-cancer vaccine: synthesis and immunological evaluation of a lipidated glycopeptide containing the tumor-associated Tn-antigen. Angew. Chem. Int. Ed. 44: 5985-5988. Selected as a VIP paper and highlighted in C&E News: Borman, S. 2005. Cancer vaccine is best in class: three-part carbohydrate vaccine elicits strong anticancer response. Chemical & Engineering News 83 (37): 10.
118. Kim, J.H., H. Yang, J. Park, and G.J. Boons. 2005. A general strategy for stereoselective glycosylations. J. Am. Chem. Soc. 127: 12090-12097. Highlighted in C&E News and Nature: Borman, S. 2005. New approach to glycosylation: technique could facilitate one-pot and automated syntheses of carbohydrates. Chemical & Engineering News 83 (34): 11. Flitsch, S.L. 2005. Synthetic chemistry: glycosylation with a twist. Nature 437 : 201-202.
117. Cato, D., T. Buskas, and G.J. Boons. 2005. Highly efficient stereospecific preparation of Tn and TF building blocks using thioglycosyl donors and the Ph 2 SO/Tf 2 O promoter system. J. Carbohydr. Chem. 24: 1-13.
116. Guan, R., A. Roychowdhury, B. Ember, S. Kumar, G.J. Boons, and R.A. Mariuzza. 2005. Crystal structure of a peptidoglycan recognition protein (PGRP) in complex with a muramyl tripeptide from Gram-positive bacteria. J. Endotoxin Res. 11(1): 41-46.
115. Siriwardena, A., H. Strachan, S. El-Daher, G. Way , B. Winchester, J. Glushka, K. Moremen, and G.J. Boons. 2005. Potent and selective inhibition of class II alpha-D-mannosidase activity by a bicyclic sulfonium salt. ChemBioChem. 6(5): 845-848.
114. Majumdar, D., G.A. Elsayed, T. Buskas, and G.J. Boons. 2005. Synthesis of proteophosphoglycans of Leishmania major and Leishmania mexicana. J. Org. Chem. 70(5): 1691-1697.
113. Roychowdhury, A., and G.J. Boons. 2005. The synthesis of diaminopimelic acid containing peptidoglycan fragments using metathesis cross couplings. Tetrahedron Lett. 46(10): 1675-1678.
112. Kim, J.H., H. Yang, and G.J. Boons. 2005. Stereoselective glycosylations using chiral auxiliaries. Angew. Chem. Int. Ed. 44: 947-949. Highlighted in Nature: Research Highlights. 2005 Nature 436 : 756-757.
111. Li, B., S. Kawatkar, S. George, H. Strachan, R.J. Woods, A. Siriwardena, K.W. Moremen, and G.J. Boons. 2004. Inhibition of Golgi mannosidase II with mannostatin A analogs: synthesis, biological evaluation and structure activity relationship studies. ChemBioChem. 5(9): 1220-1227.
110. Guan, R., A. Roychowdhury, B. Ember, S. Kumar, G.J. Boons, and R.A. Mariuzza. 2004. Structural basis for peptidoglycan binding by peptidoglycan recognition proteins. Proc. Natl. Acad. Sci. 101(49): 17168-17173.
109. Venot, A., E.E. Swayze, R.H. Griffey, and G.J. Boons. 2004. Disaccharide mimetics of the aminoglycoside antibiotic neamine. ChemBioChem. 5: 1228-1236.
108. Santhanam, B., M.A. Wolfert, J.N. Moore, and G.J. Boons. 2004. Synthesis and biological evaluation of a lipid A derivative that contains an aminogluconate moiety. Chem. Eur. J. 10: 4798-4807.
107. Santhanam, B. and G.J. Boons. 2004. Preparation of a lipid A derivative that contains a 27-hydroxyoctacosanoic moiety. Org. Lett. 6(19): 3333-3336.
106. Buskas, T., Y.H. Li, and G.J. Boons. 2004. The immunity of the tumor associated antigen Lewis (y) may be suppressed by a bifunctional cross- linker required for coupling to a carrier protein. Chem. Eur. J. 10: 3517-3524.
105. Narendran P., K. Elsegood, N.J. Leech, W.M. Macindoe, G.J. Boons, C.M. Dayan. 2004. Dendritic cell-based assays, but not mannosylation of antigen, improves detection of T-cell responses to proinsulin in type 1 diabetes. Immunology. 111: 422-429.
104. Galan, M., A. Venot, and G.J.Boons. 2004. The design and synthesis of a selective inhibitor for Fucosyltransferase VI. Org. & Biomol. Chem. 2(9): 1376-1380.
103. Galan, M., C. Dodsen, A. Venot, and G.J. Boons. 2004. Glycosyltransferase activity can be selectively modulated by chemical modificiations of acceptor substrates. Biorg. Med. Chem. Lett. 14: 2205-2208.
102. Watt, G. and G.J. Boons. 2004. A convergent strategy for the preparation of N -glycan core di, tri- and pentasaccharide thioaldoses for the site-specific glycosylation of peptides and proteins bearing free cysteines. Carbohydr. Res. 339(2): 181-193. Selected for cover picture.
101. Prabhu, A. and G.J.Boons. 2003. A new set of orthogonal protecting groups for the modular synthesis of heparan sulfate fragments. Org. Lett. 5(26): 4975-4978.
100. Galan, M.C., A.P. Venot, J. Glushka, A. Imberty, and G.J. Boons. 2003. Chemo-enzymatic synthesis of conformationally constrained oligosaccharides. Org. & Biomol. Chem. 1: 3891-3899.
99. Majumdar, D., T. Zhu, and G.J. Boons. 2003. Synthesis of oligosaccharides on soluble high-molecular-weight branched polymers in combination with purification by nanofiltration. Org. Lett. 5(20): 3591-3594.
98. Watt, G., J. Lund, M. Levens, V.S.K. Kolli, R. Jefferis, and G.J. Boons. 2003. Site-specific glycosylation of an aglycosylated human IgG1-Fc antibody protein generates neoglycoproteins with enhanced function. Chem. & Biol. 10(9): 807-814.
97. Elsayed, G.A. and G.J. Boons. 2003. Chemical synthesis of alpha-D-mannosylphosphate serine derivatives: A new class of synthetic glycopeptides. Synlett. (9): 1373-1375.
96. Thobhani, S., B. Ember, A. Siriwardena, and G.J. Boons. 2003. The role of multivalency in the mode-of-action of bacterial sialidases: Novel galactose-based inhibitors. J. Am. Chem. Soc. 125(24): 7154-7155. Highlighted in C&E News: Science Concentrates. 2003. Polyvalent ligand inhibits cholera enzyme. Chemical & Engineering News 81 (25): 38.
95. Demchenko, A., M. A. Wolfert, B. Santhanam, J. N. Moore, and G. J. Boons. 2003. Synthesis and biological evaluation of Rhizobium sin-1 lipid A derivatives. J. Am. Chem. Soc. 125(20): 6103-6112.
94. Pinhal-Enfield, G., M. Ramanathan, G. Hasko, S. N. Vogel, A. L. Salzman, G. J. Boons, and S. J. Leibovich. 2003. An angiogenic switch in macrophages involving synergy between toll-like receptors 2, 4, 7, and 9, and adenosine A2A receptors. Am. J. Path. 163(2): 711-21.
93. Galan, M.C., A.P. Venot, and G.J. Boons. 2003. Glycosyltransferase activity can be modulated by small conformational changes of acceptor substrates. Biochemistry. 42: 8522-8529.
92. De Meo, C., A. Demchenko, and G. J. Boons. 2002. Triflouroacetamido substituted sialyl donors for the preparation of sialyl galactosides. Aus. J. Chem. 55: 131-134.
91. Haller, M. F. and G. J. Boons. 2002. Selectively protected disaccharide building blocks for modular synthesis of heparin fragments (Part 2). Eur. J. Org. Chem. 2033-2038.
90. Galan, M.C., A.P. Venot, J. Glushka, A. Imberty, and G.J. Boons. 2002. Alpha-(2,6)-sialyltransferase catalyzed sialylations of conformationally constrained oligosaccharides. J. Am. Chem. Soc. 124: 5964-5973.
89. Geurtsen, R. and G.J. Boons. 2002. Regioselective glycosylations in solution and on soluble and insoluble polymeric support. Eur. J. Org. Chem. 1473-1477.
88. Elsayed, G.A., T. Zhu, and G.J. Boons. 2002. Demixing libraries of saccharides using a multi-linker approach in combination with a soluble polymeric support. Tetrahedron Lett. 43: 4691-4694.
87. Chowdhury, A., A. Siriwardena, and G.J. Boons. 2002. A highly convergent approach for the synthesis of disaccharide repeating units of peptidoglycan. 2002. Tetrahedron Lett. 7806-7807.
86. Wolfert, M.A., T.F. Murray, G.J. Boons, and J.N. Moore. 2002. The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan. J. Biol. Chem. 42(277): 39179-39186.
85. Arranz-Plaza, E., A.S. Tracy, A. Siriwardena, J.M. Pierce, and G.J. Boons. 2002. High avidity, low affinity multivalent interactions and the block to polyspermy. J. Am. Chem. Soc. 124(44): 13035-13046.
84. Geurtsen, R. and G.J. Boons. 2002. Chemoselective glycosylations of sterically hindered glycosyl acceptors. Tetrahedron Lett. 43: 9429-9431.
83. Clarke, C., R.J. Woods, J. Glushka, A. Cooper, M. A. Nutley, and G. J. Boons. 2001. The involvement of water in carbohydrate-protein binding. J. Am. Chem. Soc. 123(49): 12238-12247.
82. Zhu, T. and G.J. Boons. 2001. Thioglycosides protected as trans-2,3-cyclic carbonates in chemoselective glycosylations. Org. Lett. 3(26): 4201-4203.
81. Kearns, D.B., A. Venot, P.J. Bonner, B. Stevens, G. J. Boons, and L.J. Shimkets. 2001. Identification of a developmental chemoattractant in Myxococcus xanthus through metabolic engineering. P. Natl. Acad. Sci. USA. 98(24): 13990-13994.
80. Arranz, E. and G. J. Boons. 2001. The 2-(Allyloxy)phenyl acetyl ester as a new relay protecting group for oligosaccharide synthesis. Tetrahedron Lett. 42(37): 6469-6471.
79. Siriwardena, A., M. Jørgensen, M.A. Wolfert, N.L. Vandenplas, J.N. Moore, and G.J. Boons. 2001. Synthesis and proinflammatory effects of peptidoglycan-derived neoglycopeptide polymers. J. Am. Chem. Soc. 123(33): 8145-8146.
78. De Meo, C., A. Demchenko, and G.J. Boons. 2001. A stereoselective approach for the synthesis of alpha-sialosides. J. Org. Chem. 66: 5490-5497.
77. McWatt, M. and G. J. Boons. 2001. Parallel combinatorial synthesis of dendrimers and their hydrogelation properties. Eur. J. Org. Chem. 2535-2545.
76. Zhu, T. and G.J. Boons. 2001. A highly efficient synthetic strategy for polymeric support synthesis of Le(x), Le(y), and H-type 2 oligosaccharides. Chem. Eur. J. 7(11): 2382-2389.
75. Demchenko, A., and G.J. Boons. 2001. A highly convergent synthesis of a complex oligosaccharide derived from group B Type III streptococcus. J. Org. Chem. 66(8): 2547-2554.
74. Haller, M. and G. J. Boons. 2001. Toward a modular approach for heparin synthesis. Perkin Transactions I. 814-822.
73. Zhu, T. and G.J. Boons. 2000. A new set of orthogonal protecting groups for oligosaccharide synthesis on a polymeric support. Tetrahedron Asymmetry 11: 199-205.
72. Reichel, F., M.C. Feiters, and G.J. Boons. 2000. Synthesis and supramolecular characterization of a novel class of glycopyranosyl containing amphiphiles that form tubular structures. J. Org. Chem. 65: 3357-3366.
71. Belogi, G., T. Zhu, and G. J. Boons. 2000. Polystyrylboronic acid as a re-useable polymeric support for oligosaccharide synthesis. Tetrahedron Lett. 41: 6965-6968.
70. Belogi, G., T. Zhu, and G. J. Boons. 2000. Polymer-supported oligosaccharide synthesis by a loading-release-reloading strategy. Tetrahedron Lett. 41: 6969-6972.
69. Zhu, T. and G. J. Boons. 2000. A novel and efficient synthesis of a dimeric Le (x) oligosaccharide on polymeric support. J. Am. Chem. Soc. 41: 10222-10223.
68. Zhu, T. and G. J. Boons. 2000. Intermolecular aglycon transfer of ethyl thioglycosides can be prevented by judicious choice of protecting groups. Carbohydr. Res. 329: 709-715.
67. Bai, Y., A. Burton, M. Johnson, and G.J. Boons. 2000. Vinyl glycosides in oligosaccharide synthesis. 6.: 3-buten-2-yl 2-azido-2-deoxy glycosides and 3-buten-2-yl-phthalimido-2-deoxy glycosides as novel glycosyl donors. J. Carbohydr. Chem. 19(7): 939-958.
66. Boons, G.J. and A. Demchenko. Recent advances in O-sialylation. 2000. Chem. Rev. 100(12): 4539-4565.
65. Demchenko, A.V. and G.J. Boons. 1999. A novel direct glycosylation approach for the synthesis of dimers of N-acetylneuraminic acid. Chem. Eur. J. 5: 1278-1283.
64. Navarre, N., N. Amiot, A. van Oijen, A. Imberty, A. Poveda, J. Jiménez-Barbero, A. Cooper, M.A. Nutley, and G.J. Boons. 1999. Synthesis and conformational analysis of a conformationally constrained trisaccharide and complexation properties with concanavalin A. Chem. Eur. J. 5: 2281-2294.
63. Demchenko, A.V., E. Rousson, and G.J. Boons. 1999. Stereoselective 1,2-cis-galactosylation assisted by remote neighboring group participation and solvent effects. Tetrahedron Lett. 40: 6523-6526.
62. Reichel, F., A.M. Roelofsen, H.P.M. Geurts, T.I. Hämäläinen, M.C. Feiters, and G.J. Boons. 1999. Stereochemical dependence of the self-assembly of the immunoadjuvants Pam3Cys and Pam3Cys-Ser. J. Am. Chem. Soc. 121: 7989-7997.
61. Zhu, T. and G.J. Boons. 1999. A two directional and highly convergent approach for the synthesis of the tumor-associated antigen globo-H. Angew. Chem. Int. Ed. 38: 3495-3497.
60. Geurtsen, R., F. Côté, M.G. Hahn, and G.J. Boons. 1999. A novel chemoselective glycosylation strategy for the rapid convergent assembly of phytoalexin-elicitor active oligosaccharides and their photo-reactive derivatives. J. Org. Chem. 64: 7828-7835.
59. Boons, G. J. 1999. Combinatorial approaches in oligosaccharide synthesis. Carbohydrates in Europe. 27: 28-32.
58. Zhu, T. and G.J. Boons. 1998. Two-directional, convergent synthesis of a pentasaccharide that is involved in the hyperacute rejection response in xenotransplantation from pig to man. J. Chem. Soc. , Perkin Trans. I. 857-861.
57. Zhu, T. and G.J. Boons. 1998. A two directional glycosylation strategy for the convergent assembly of oligosaccharides. Tetrahedron Lett. 39: 2187-2190.
56. Macindoe, W.M., A.H. Van Oijen, and G.J. Boons. 1998. A unique and highly facile method for synthesizing disulfide linked neoglycoconjugates: A new approach for remodelling of peptides and proteins. Chem. Commun. 847-848.
55. Demchenko, A.V. and G.J. Boons. 1998. A novel and versatile glycosyl donor for the preparation of glycosides of N-Acetylneuraminic acid. Tetrahedron Lett. 39: 3065-3068.
54. Zhu, T. and G.J. Boons. 1998. A two-directional approach for the solid-phase synthesis of trisaccharide libraries. Angew. Chem. Int. Ed. 37: 1898-1900.
53. Bowers, S.G., D.M. Coe, and G.J. Boons. 1998. Application of the 2,5-dimethylpyrrole group as a new and orthogonal amine-protecting group in oligosaccharide synthesis. J. Org. Chem. 63: 4570-4571.
52. Reichel F. and G.J. Boons. 1998. Sweet promise. Chemistry in Britain. 34: 43-46.
51. Johnson, M., C. Arles, and G.J. Boons. 1998. Vinyl glycosides in oligosaccharide synthesis .5. A latent-active blycosylation strategy for the preparation of branched trisaccharide libraries. Tetrahedron Lett. 39: 9801-9804.
50. Demchenko, A. and G.J. Boons. 1997. A highly convergent synthesis of a hexasaccharide derived from the oligosaccharide of group B type III Streptococcus. Tetrahedron Lett. 38: 1629-1632.
49. Navarre, N., A.H.van Oijen, and G.J. Boons. 1997. The design and synthesis of a conformationally constrained trisaccharide for probing carbohydrate-protein interactions. Tetrahedron Lett. 38: 2023-2026.
48. Boons, G.J., S. Bowers, and D.M. Coe. 1997. Trityl ethers in oligosaccharide synthesis: A novel strategy for the convergent assembly of oligosaccharides. Tetrahedron Lett. 38: 3773-3776.
47. Burton, A., P. Wyatt, and G.J. Boons. 1997. Preparation of fluorinated galactosyl nucleoside diphosphates to study the mechanism of the enzyme galactopyranose mutase. J. Chem. Soc., Perkin Trans. 2375-2382.
46. Demchenko, A., T. Stauch, and G.J. Boons. 1997. Solvent and other effects on the stereoselectivity of thioglycoside glycosidations. Synlett. 818-820.
45. Boons, G.J. and T. Zhu. 1997. Novel regioselective glycosylations for the convergent and chemoselective assembly of oligosaccharides. Synlett. 809-811.
44. Gibson, R.R., R.P. Dickinson, and G.J. Boons. 1997. Vinyl glycosides in oligosaccharide synthesis .4. glycosidase-catalysed preparation of substituted allyl glycosides. J. Chem. Soc., Perkin Trans. 3357-3360.
43. Reichel, F., P.R. Ashton, and G.J. Boons. 1997. Synthetic carbohydrate-based vaccines: Synthesis of an L-glycero-D-manno-heptose antigen-T-epitope-lipopeptide conjugate. Chem. Commun. 2087-2088.
42. Geurtsen, R., D.S. Holmes, and G.J. Boons. 1997. Chemoselective glycosylations .2. Differences in size of anomeric leaving groups can be exploited in chemoselective glycosylations. J. Org. Chem. 62: 8145-8154.
41. Boons, G.J., A. Burton, and S. Isles. 1996. A new procedure for the isomerisation of substituted and unsubstituted allyl ethers of carbohydrates. Chem. Commun. 141-142.
40. Boons, G.J. 1996. Strategies in oligosaccharide synthesis. Tetrahedron. 52: 1095-1121.
39. Parsons, N.J., G.J. Boons, P.R. Ashton, P.D. Redfern, P. Quirk, Y. Gao, C. Constantinidou, J. Patel, J. Bramley, J.A. Cole, and H. Smith. 1996. Lactic acid is the factor in blood cell extracts which enhances the ability of CMP-NANA to sialylate gonococcal lipopolysaccharide and induce serum resistance. Microbial Parthogenesis. 20: 87-100.
38. Boons, G.J., A. Burton, and P. Wyatt. 1996. Glycosyl phosphates: A new latent-active anomeric phosphorylation strategy. Synlett. 310-312.
37. Boons, G.J., R. Eveson, S. Smith, and T. Stauch. 1996. A critical evaluation of the cationic coupling of 4-acetoxy-1,3-dioxanes. Synlett. 536-538.
36. Boons, G.J. 1996. Recent developments in chemical oligosaccharide synthesis. Contemp. Org. Synth. 3: 173-200.
35. Boons, G.J. and S. Isles. 1996. Vinyl glycosides in oligosaccharide synthesis .2. The use of allyl and vinyl glocosides in oligosaccharide synthesis. J. Org. Chem. 61: 4262-4271.
34. Boons, G.J. 1996. Synthetic oligosaccharides: recent advances. Drug Discovery Today. 1: 331-342.
33. Boons, G.J. and T. Stauch. 1996. Stereoselectivity in glycosidic bond formation: Studies on the anomerisataion of thioglycosides. Synlett. 906-908.
32. Boons, G.J., B. Heskamp, and F. Hout. 1996. Vinyl glycosides in oligosaccharide synthesis: A strategy for the preparation of trisaccharide libraries based on latent-active glycosylation. Angew. Chem. Int. Ed. Engl. 35: 2845-2847.
31. Boons, G.J., J.A. Clase, I.C. Lennon, S.V. Ley, and J. Staunton. 1995. Biosynthesis of tetronasin .4. Preparation of deuterium labelled C19-C26, C17-C26, C11-C26 and C3-C26 polyketide fragments as putative bisynthetic precursors of the ionophore antibiotic tetronasin (ICI 139603). Tetrahedron. 51: 5417-5446.
30. Boons, G.J., S. Isles, and P. Setälä. 1995. An improved procedure for the preparation of 1,6-anhydro sugars. Synlett. 755-756.
29. Boons, G.J., R. Geurtsen, and E. Holmes. 1995. Chemoselective glycosylations .1. Differences in size of anomeric leaving groups can be exploited in chemoselective glycosylations. Tetrahedron Lett. 36: 6325-6328.
28. Boons, G.J., D.S. Brown, J.A. Clase, I.C. Lennon, and S.V. Ley. 1994. Two new routes to the C19-C26 tetrahydrofuran fragment of the acyl tetronic acid ionophore tetronasin (ICI M139603). Tetrahedron Lett. 35: 319-322.
27. Boons, G.J., I.C. Lennon, S.V. Ley, E.S.E. Owen, J. Staunton, and D.J. Wadsworth. 1994. Novel polyene cyclisation routes to the acyl tetronic acid ionophore tetronasin (ICI M139603). Tetrahedron Lett. 35: 323-326.
26. Boons, G.J., R. Downham, K.S. Kim, S.V. Ley, and M. Woods. 1994. Dispiroketals in synthesis .10. Further reactions of dispoke protected lactate and glycolate enolates. Tetrahedron. 50: 7157-7176.
25. Boons, G.J. and S. Isles. 1994. Vinyl glycosides in oligosaccharide synthesis .1. A new latent-active glycosylation strategy. Tetrahedron Lett. 35: 3593-3596.
24. Ley, S.V., G.J. Boons, R. Leslie, M. Woods, and D.M. Hollinshead. 1993. Dispiroketals in synthesis .3. Selective protection of diequatorial vicinal diols in carbohydrates. Synthesis. 689-692.
23. Boons, G.J., D.A. Entwistle, S.V. Ley, and M. Woods. 1993. Dispiroketals in synthesis .4. Enantioselective desymmertrization of glycerol using a C 2 -symmetric disubstituted bis -dihydropyran. Tetrahedron Lett. 34: 5649-5652.
22. Smid, P., F.J.M. Schippers, H.J.G. Broxterman, G.J.P.H. Boons, G.A. van der Marel, and J.H. van Boom. 1993. Use of (chloromethyl)dimethylphenylsilane in sugar chemistry. Stereo-controlled approach to destomic acid and 1-deoxy-nojirimycin. Recl. Trav. Chim. Pays-Bas. 112: 451-456.
21. Boons, G.J., P. Grice, R. Leslie, S.V. Ley, and L.L. Yeung. 1993. Dispiroketals in synthesis .5. A new opportunity for oligosaccharide synthesis using differentially activated glycosyl donors and acceptors. Tetrahedron Lett. 34: 8523-8526.
20. Boons, G.J., G.H. Castle, J.A. Clase, P. Grice, S.V. Ley, and C. Pinel. 1993. Selective acylation and alkylation reactions of diols using dibutyltin dimethoxide. Synlett. 913-914.
19. Boons, G.J.P.H., F.L. van Delft, P.A.M. van der Klein, G.A. van der Marel, and J.H. van Boom. 1992. Synthesis of lD-Hep p and KDO containing di- and tetrasaccharide derivatives of Neisseria meningitidis inner-core region via iodonium ion promoted glycosidations. Tetrahedron. 48: 885-904.
18. Boons, G.J.P.H., M. Overhand, G.A. van der Marel, and J.H. van Boom. 1992. Synthesis of two branched heptopyranoside ( lD-Hep p ) containing trisaccharides of the inner-core region of Citrobacter PCM 1487. Recl. Trav. Chim. Pays-Bas. 111: 144-148.
17. Van der Klein, P.A.M., W. Filemon, G.J.P.H. Boons, G.H. Veeneman, G.A. van der Marel, and J.H. van Boom. 1992. Synthesis of a cell wall component of Haemophilus (Actionobacillus) Pleuropneumoniae serotype 5. Tetrahedron. 48: 4649-4658.
16. Noort, D., N.C.R. van Straten, G.J.P.H. Boons, G.A. van der Marel, X. Bossuyt, N. Blanckaert, G.J. Mulder, and J.H. van Boom. 1992. Synthesis of potential UDP-glycoronosyltransferase inhibitors. Biomed. Chem. Lett. 2: 583-588.
15. Smid, P. W.P.A. Jörning, A.M.G. van Duuren, G.J.P.H. Boons, G. A. van der Marel, and J.H. van Boom. 1992. Stereoselective synthesis of a dimer containing an alpha-linked 2-acetamido-4-amino-2,4,6-trideoxy-D-galactopyranose (sugp) unit J. Carbohydrate Chem. 11: 849-865.
14. Verheul, A.F.M., H. Snippe, J. Verhoef, P. Hoogerhout, J.T. Poolman, G.J.P.H. Boons, G.A. van der Marel, and J.H. van Boom. 1991. Immunogenicity of meningococcal LPS derived oligosaccharide-protein conjugates using isolated and synthetic oligosaccharides. Neisseriae, Proc. Int. Pathog. Neisserria Conf. 7th Meeting 1990, (M.A. de Gruyter, ed.) Berlin, Germany.
13. Boons, G.J.P.H., R. Steyger, M. Overhand, G.A. van der Marel, and J.H. van Boom. 1991. Synthesis of naturally occurring lD-Hep p containing disaccharides. J. Carbohydrate Chem. 10: 995-1007.
12. Boons, G.J.P.H., P. Hoogerhout, J.T. Poolman, G.A. van der Marel, and J.H. van Boom. 1991. Preparation of a well-defined sugar-peptide conjugate: a possible approach to a synthetic vaccine against Neisseria meningitidis. Biomed. Chem. Lett. 1: 303-308.
11. Verheul, A.F.M., G.J.P.H. Boons, G.A. van der Marel, J.H. van Boom, H.J. Jennings, H. Snippe, J. Verhoef. P. Hoogerhout, and J.T. Poolman. 1991. Minimal oligosaccharide structure required for induction of immune responses against meningococcal L1, L2, and L3,7,9 lipopolysaccharides determined by using synthetic oligosaccharide-protein conjugates. Infect. Immun. 59: 3566-3573.
10. Boons, G.J.P.H., P.A.M. van der Klein, G.A. van der Marel, and J.H. van Boom. 1990. A practical route toward the preparation of 4,5:7,8-di- O-isopropylidene KDO ethyl ester. Recl. Trav. Chim. Pays-Bas. 109: 273-276.
9. Boons, G.J.P.H., C.J.J. Elie, G.A. van der Marel, and J.H. van Boom. 1990. Use of (phenyldimethylsilyl)methoxymethyl and (phenyldimethylsilyl)methyl ethers as protecting groups for sugar hydroxyls. Tetrahedron Lett. 31: 2197-2200.
8. van der Klein P.A.M., G.J.P.H. Boons, G.H. Veeneman, G.A. van der Marel, and J.H. van Boom. 1990. Iodonium ion promoted cyclization: a convenient approach to glycosyl donors of 3-deoxy-D-manno-2-octulosonic acid (KDO). Synlett. 311-313.
7. Noort, D., G.H. Veeneman, G.J.P.H. Boons, G.A. van der Marel, G.J. Mulder, and J.H. van Boom. 1990. Iodonium ion promoted reactions at the anomeric C-2 centre of 1-methylene sugars. Synlett. 205-206.
6. Boons, G.J.P.H., G.A. van der Marel, J.T. Poolman, and J.H. van Boom. 1989. Synthesis of l-glycero-alpha-D-manno-heptopyranose-containing disaccharide derivatives of the Neisseria meningtitidis dephosphorylated inner-core region. Recl. Trav. Chim. Pays-Bas. 108: 339-343.
5. Boons, G.J.P.H., G.A. van der Marel, and J. H. van Boom. 1989. A versatile and new highly stereoselective approach to the synthesis of l- glycero-D-manno-heptopyranosides. Tetrahedron Lett. 30: 229-232.
4. Boons, G.J.P.H., M. Overhand, G.A. van der Marel, and J.H. van Boom. 1989. Synthesis of a trisaccharide of the inner core region of Citrobacter PCM 187 lipopolysaccharide that contains l-glycero-alpha-D-manno-heptopyranosyl units. Carbohydr. Res. 192: c1-c4.
3. Boons, G.J.P.H., M. Overhand, G.A. van der Marel, and J.H. van Boom. 1989. Application of the dimethyl(phenyl)silyl group as a masked form of the hydroxy group in the synthesis of an l-glycero-alpha-D-manno-heptopyranoside-containing trisaccharide from the dephosphorylated inner core region of Neisseria meningitidis. Angew. Chem. Int. Ed. Engl. 28: 1504-1506.
2. van der Klein, P.A.M., G.J.P.H. Boons, G.H. Veeneman, G.A. van der Marel, and J. H. van Boom. 1989. An efficient route to 3-deoxy-D- manno-2-octulosonic acid (KDO) derivatives via a 1,4-cyclic sulfate approach. Tetrahedron Lett. 30: 5477-5480.
1. Boons, G.J.P.H., P.A.M. van der Klein, G.A. van der Marel, and J. H. van Boom. 1988. Synthesis of L-glycero-D-manno-heptose. Recl. Trav. Chim. Pays-Bas. 107: 507-508.
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